Overview

  • Product name
  • Description
    Rabbit polyclonal to SLITRK6
  • Specificity
    This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
  • Tested applications
    Suitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 16 amino acid synthetic peptide from near the carboxy terminus of human SLITRK6.

  • Positive control
    • SK-N-SH cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab67312 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 95 kDa).

Target

  • Function
    Suppresses neurite outgrowth.
  • Tissue specificity
    In adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors.
  • Sequence similarities
    Belongs to the SLITRK family.
    Contains 11 LRR (leucine-rich) repeats.
    Contains 2 LRRCT domains.
    Contains 2 LRRNT domains.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4832410J21Rik antibody
    • DFNMYP antibody
    • MGC119595 antibody
    • MGC119596 antibody
    • MGC119597 antibody
    • OTTHUMP00000066012 antibody
    • SLIK6_HUMAN antibody
    • SLIT and NTRK like family member 6 antibody
    • SLIT and NTRK like protein 6 antibody
    • SLIT and NTRK-like protein 6 antibody
    • Slit and trk like 6 antibody
    • Slit and trk like gene 6 antibody
    • SLITRK 6 antibody
    • Slitrk6 antibody
    see all

Images

  • Lane 1 : Anti-SLITRK6 antibody (ab67312) at 0.5 µg/ml
    Lane 2 : Anti-SLITRK6 antibody (ab67312) at 1 µg/ml

    Lane 1 : SK-N-SH cell lysate
    Lane 2 : SK-N-SH cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 95 kDa
    Observed band size : 95 kDa
    Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.
  • Immunofluorescence of Slitrk6 in Human Brain cells using ab67312 at 20 ug/ml.

References

This product has been referenced in:
  • Li H  et al. Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells. Cancer Lett 297:198-206 (2010). WB ; Human . Read more (PubMed: 20547442) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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