The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 95 kDa).
FunctionSuppresses neurite outgrowth.
Tissue specificityIn adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors.
Sequence similaritiesBelongs to the SLITRK family. Contains 11 LRR (leucine-rich) repeats. Contains 2 LRRCT domains. Contains 2 LRRNT domains.