Overview

  • Product nameAnti-SLPI antibody [31] (Biotin)
    See all SLPI primary antibodies
  • Description
    Mouse monoclonal [31] to SLPI (Biotin)
  • ConjugationBiotin
  • SpecificityThe reactivity of the antibody with the isolated domains was evaluated using isolated domains of SLPI obtained by cleavage using partial acidic hydrolysis. Therefore, it is possible that the antibody will recognize other SLPI cleavage products generated by e.g. (microbial) proteases.
  • Tested applicationsSuitable for: IHC-Fr, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human antileukoprotease (ALP)

Properties

Applications

Our Abpromise guarantee covers the use of ab17158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/10.
IHC-P Use at an assay dependent dilution.
WB 1/10. Predicted molecular weight: 12 kDa.

Target

  • FunctionAcid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues.
  • Tissue specificityMucous fluids.
  • Sequence similaritiesContains 2 WAP domains.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALK 1 antibody
    • ALK1 antibody
    • ALP antibody
    • Antileukoprotease antibody
    • Antileukoproteinase 1 antibody
    • Antileukoproteinase antibody
    • Antileukoproteinase1 antibody
    • BLPI antibody
    • Human seminal protease inhibitor antibody
    • HUSI 1 antibody
    • HUSI antibody
    • HUSI I antibody
    • HUSI-1 antibody
    • MPI antibody
    • Mucus proteinase inhibitor antibody
    • Protease inhibitor WAP4 antibody
    • Secretory leukocyte peptidase inhibitor antibody
    • Secretory leukocyte protease inhibitor antibody
    • Seminal proteinase inhibitor antibody
    • SLPI antibody
    • SLPI_HUMAN antibody
    • WAP four disulfide core domain protein 4 antibody
    • WAP four-disulfide core domain protein 4 antibody
    • WAP4 antibody
    • WFDC4 antibody
    see all

References for Anti-SLPI antibody [31] (Biotin) (ab17158)

This product has been referenced in:
  • Skrzeczynska-Moncznik J  et al. Secretory leukocyte proteinase inhibitor-competent DNA deposits are potent stimulators of plasmacytoid dendritic cells: implication for psoriasis. J Immunol 189:1611-7 (2012). IHC ; Human . Read more (PubMed: 22786767) »

See 1 Publication for this product

Product Wall

We forwarded your question to an expert in this field and this is the answer I received: The reactivity of the antibody with the isolated domains was evaluated using isolated domains of SLPI obtained by cleavage using partial acidic hydrolysis. Ther...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"