Anti-Smac / Diablo antibody [79-1-83] (ab69509)

Overview

  • Product nameAnti-Smac / Diablo antibody [79-1-83]
    See all Smac / Diablo primary antibodies
  • Description
    Mouse monoclonal [79-1-83] to Smac / Diablo
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human, Monkey
  • Immunogen

    Recombinant full length human Smac/DIABLO

  • Positive control
    • 293, Hela, Jurkat, Vero cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab69509 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1 µg/ml (developed by ECL). Detects a band of approximately 22 kDa (predicted molecular weight: 27 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPromotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).
    • Tissue specificityUbiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes.
    • DomainThe mature N-terminus mediates interaction with XIAP.
    • Cellular localizationMitochondrion. Released into the cytosol when cells undergo apoptosis.
    • Information by UniProt
    • Database links
    • Alternative names
      • 0610041G12Rik antibody
      • DBLOH_HUMAN antibody
      • DBOH antibody
      • DFNA64 antibody
      • diablo antibody
      • Diablo homolog (Drosophila) antibody
      • Diablo homolog antibody
      • Diablo homolog mitochondrial antibody
      • Diablo IAP binding mitochondrial protein antibody
      • Diablo like protein antibody
      • DIABLO S antibody
      • Direct IAP binding protein with low pI antibody
      • Direct IAP-binding protein with low pI antibody
      • FLJ10537 antibody
      • FLJ25049 antibody
      • mitochondrial antibody
      • Mitochondrial Smac protein antibody
      • Second mitochondria derived activator of caspase antibody
      • Second mitochondria-derived activator of caspase antibody
      • SMAC 3 antibody
      • Smac antibody
      • Smac protein antibody
      • SMAC3 antibody
      see all

    Anti-Smac / Diablo antibody [79-1-83] images

    • All lanes : Anti-Smac / Diablo antibody [79-1-83] (ab69509) at 1 µg/ml

      Lane 1 : MW marker
      Lane 2 : 293 cell lysate
      Lane 3 : Hela cell lysate
      Lane 4 : Jurkat cell lysate
      Lane 5 : Vero cell lysate

      Developed using the ECL technique

      Predicted band size : 27 kDa
      Observed band size : ~22 kDa (why is the actual band size different from the predicted?)

    References for Anti-Smac / Diablo antibody [79-1-83] (ab69509)

    ab69509 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"