Anti-Smad3 antibody [EP568Y] (ab40854)

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ab40854 has been referenced in 48 publications.

  • Zhang X  et al. ING5 is a Potential Target for Osteosarcoma Therapy. Technol Cancer Res Treat 17:1533033818762680 (2018). PubMed: 29528777
  • Xu G  et al. Colon cancers carrying BRAF V600E and ß-catenin T41A activating mutations are resistant to numerous common anticancer drugs. Oncol Lett 15:4471-4476 (2018). PubMed: 29541216
  • Zhang P  et al. Salidroside Inhibits Myogenesis by Modulating p-Smad3-Induced Myf5 Transcription. Front Pharmacol 9:209 (2018). PubMed: 29593538
  • Wang Y  et al. Notch signaling mediated by TGF-ß/Smad pathway in concanavalin A-induced liver fibrosis in rats. World J Gastroenterol 23:2330-2336 (2017). WB . PubMed: 28428712
  • Han Y  et al. Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis. PLoS One 12:e0166014 (2017). IF ; Mouse . PubMed: 28135282
  • Yue L  et al. Efficacy of ALK5 inhibition in myelofibrosis. JCI Insight 2:e90932 (2017). WB ; Human . PubMed: 28405618
  • Lefebvre P  et al. Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARa-regulated dermatopontin. JCI Insight 2:N/A (2017). WB ; Mouse . PubMed: 28679947
  • Shen J  et al. DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism. JCI Insight 2:N/A (2017). WB ; Mouse, Human . PubMed: 28614801
  • Xue R  et al. Polycaprolactone nanofiber scaffold enhances the osteogenic differentiation potency of various human tissue-derived mesenchymal stem cells. Stem Cell Res Ther 8:148 (2017). WB ; Human . PubMed: 28646917
  • Sun Q  et al. ENMD-1068 inhibits liver fibrosis through attenuation of TGF-ß1/Smad2/3 signaling in mice. Sci Rep 7:5498 (2017). PubMed: 28710422
  • Nie J  et al. Adipocytes promote cholangiocarcinoma metastasis through fatty acid binding protein 4. J Exp Clin Cancer Res 36:183 (2017). WB ; Human . PubMed: 29237483
  • Regan JN  et al. Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model. Front Endocrinol (Lausanne) 8:358 (2017). PubMed: 29312148
  • Mears AJ  et al. Mining the transcriptome for rare disease therapies: a comparison of the efficiencies of two data mining approaches and a targeted cell-based drug screen. NPJ Genom Med 2:14 (2017). PubMed: 29263829
  • Gong Y  et al. Low density lipoprotein - rosiglitazone - chitosan-calcium alginate/nanoparticles inhibition of human tenon's fibroblasts activation and proliferation. Oncotarget 8:105126-105136 (2017). PubMed: 29285239
  • Zhang S  et al. Tumor-associated macrophages promote tumor metastasis via the TGF-ß/SOX9 axis in non-small cell lung cancer. Oncotarget 8:99801-99815 (2017). WB ; Human . PubMed: 29245941
  • Zeng X  et al. Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells. Oncotarget 8:72872-72885 (2017). PubMed: 29069832
  • Lv C  et al. MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists. Nat Commun 8:1036 (2017). PubMed: 29051494
  • Shang P  et al. Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-ß1. Mol Med Rep 16:4537-4544 (2017). PubMed: 28791353
  • Wang J  et al. Metformin ameliorates skeletal muscle insulin resistance by inhibiting miR-21 expression in a high-fat dietary rat model. Oncotarget 8:98029-98039 (2017). WB, ICC/IF ; Rat . PubMed: 29228671
  • Zeeh F  et al. Proteinase-activated receptor 2 promotes TGF-ß-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-ß type I receptor ALK5. Oncotarget 7:41095-41109 (2016). PubMed: 27248167
  • Liu P  et al. MicroRNA-23a regulates epithelial-to-mesenchymal transition in endometrial endometrioid adenocarcinoma by targeting SMAD3. Cancer Cell Int 16:67 (2016). WB . PubMed: 27601936
  • Chen JL  et al. Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia. Cancer Res 76:5372-82 (2016). PubMed: 27328730
  • Wu Q  et al. miR-489 inhibits silica-induced pulmonary fibrosis by targeting MyD88 and Smad3 and is negatively regulated by lncRNA CHRF. Sci Rep 6:30921 (2016). WB ; Mouse . PubMed: 27506999
  • Zhang X  et al. Puerarin Attenuates Cardiac Hypertrophy Partly Through Increasing Mir-15b/195 Expression and Suppressing Non-Canonical Transforming Growth Factor Beta (Tgfß) Signal Pathway. Med Sci Monit 22:1516-23 (2016). WB . PubMed: 27145790
  • Omata M  et al. Hepatocyte Nuclear Factor-1ß Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells. PLoS One 11:e0154912 (2016). WB . PubMed: 27196561
  • Li SC  et al. Microarray Study of Pathway Analysis Expression Profile Associated with MicroRNA-29a with Regard to Murine Cholestatic Liver Injuries. Int J Mol Sci 17:324 (2016). PubMed: 26938532
  • Shang P  et al. Acetyl-11-Keto-ß-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-ß1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats. Sci Rep 6:39809 (2016). WB . PubMed: 28009003
  • Li Y  et al. Genetic depletion and pharmacological targeting of av integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models. Breast Cancer Res 17:28 (2015). PubMed: 25849225
  • Chen JL  et al. Development of novel activin-targeted therapeutics. Mol Ther 23:434-44 (2015). PubMed: 25399825
  • Marino FE  et al. Activin-ßC modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways. J Cachexia Sarcopenia Muscle 6:365-80 (2015). WB ; Mouse . PubMed: 26673867
  • Bartscht T  et al. Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action. Mol Cancer 14:199 (2015). PubMed: 26588899
  • Huang YH  et al. Activation of Mir-29a in Activated Hepatic Stellate Cells Modulates Its Profibrogenic Phenotype through Inhibition of Histone Deacetylases 4. PLoS One 10:e0136453 (2015). WB ; Human . PubMed: 26305546
  • Aspalter IM  et al. Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. Nat Commun 6:7264 (2015). PubMed: 26081042
  • Waning DL  et al. Excess TGF-ß mediates muscle weakness associated with bone metastases in mice. Nat Med 21:1262-1271 (2015). PubMed: 26457758
  • Ungefroren H  et al. Rac1b negatively regulates TGF-ß1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling. Oncotarget 5:277-90 (2014). PubMed: 24378395
  • Marino FE  et al. The inhibin/activin signalling pathway in human gonadal and adrenal cancers. Mol Hum Reprod 20:1223-37 (2014). PubMed: 25180271
  • Cho SY  et al. The prognostic significance of Smad3, Smad4, Smad3 phosphoisoform expression in esophageal squamous cell carcinoma. Med Oncol 31:236 (2014). PubMed: 25267569
  • Chen RY  et al. Effect of oridonin-mediated hallmark changes on inflammatory pathways in human pancreatic cancer (BxPC-3) cells. World J Gastroenterol 20:14895-903 (2014). WB ; Human . PubMed: 25356049
  • Isogaya K  et al. A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression. Cell Res 24:994-1008 (2014). PubMed: 25060702
  • Wei X  et al. Kindlin-2 Mediates Activation of TGF-ß/Smad Signaling and Renal Fibrosis. J Am Soc Nephrol 24:1387-98 (2013). Human . PubMed: 23723426
  • Nakajima T  et al. Temporal and regional patterns of Smad activation in the rat hippocampus following global ischemia. J Neurol Sci N/A:N/A (2013). WB, IHC ; Rat . PubMed: 24290497
  • Zheng J  et al. Activation of hepatic stellate cells is suppressed by microRNA-150. Int J Mol Med 32:17-24 (2013). PubMed: 23604143
  • Kim SH  et al. Smad3 and its phosphoisoforms are prognostic predictors of hepatocellular carcinoma after curative hepatectomy. Hepatobiliary Pancreat Dis Int 11:51-9 (2012). IHC ; Human . PubMed: 22251470
  • Zieba A  et al. Intercellular variation in signaling through the TGF-ß pathway and its relation to cell density and cell cycle phase. Mol Cell Proteomics 11:M111.013482 (2012). PubMed: 22442258
  • Kohn EA  et al. Biological Responses to TGF-ß in the Mammary Epithelium Show a Complex Dependency on Smad3 Gene Dosage with Important Implications for Tumor Progression. Mol Cancer Res 10:1389-99 (2012). PubMed: 22878587
  • González AM  et al. Assessment of the protective effects of oral tocotrienols in arginine chronic-like pancreatitis. Am J Physiol Gastrointest Liver Physiol 301:G846-55 (2011). WB ; Rat . PubMed: 21852363
  • Wang QL  et al. Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro. BMC Cell Biol 11:31 (2010). WB . PubMed: 20441599
  • Wu R  et al. Derivation, characterization and differentiation of a new human embryonic stem cell line from a Chinese hatched blastocyst assisted by a non-contact laser system. Hum Cell 23:89-102 (2010). Human . PubMed: 20973834


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