Overview

  • Product name
  • Description
    Rabbit polyclonal to SMG5
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A region between residues 400-450 of Human SMG5 (NP_056142.2).

  • Positive control
    • Jurkat lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab100798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Relevance
      SMG5 plays a role in nonsense mediated mRNA decay. It promotes dephosphorylation of RENT1, and is necessary for TERT activity. It is part of a complex that contains SMG1, SMG5, SMG7, PP2AC, a short isoform of UPF3A (isoform UPF3AS, but not isoform UPF3AL) and phosphorylated RENT1/UPF1.
    • Cellular localization
      Cytoplasmic and Nuclear
    • Database links
    • Alternative names
      • EST1 like protein B antibody
      • EST1B antibody
      • LPTS interacting protein antibody
      • LPTS RP1 antibody
      • Nonsense mediated mRNA decay factor antibody
      see all

    Images

    • Staining of Human SMG5 in Jurkat cell lysate immunoprecipitated using 100798 at 3 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Exposure time: 10 seconds

    References

    ab100798 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab100798.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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