Overview

  • Product name
  • Description
    Rabbit polyclonal to SMNDC1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1-178 of SMNDC1

  • Positive control
    • A431, H1299 and HeLa cell lysates; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab155021 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 32 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Necessary for spliceosome assembly. Overexpression causes apoptosis.
  • Tissue specificity
    Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.
  • Sequence similarities
    Belongs to the SMN family.
    Contains 1 Tudor domain.
  • Cellular localization
    Nucleus speckle. Nucleus > Cajal body. Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.
  • Information by UniProt
  • Database links
  • Alternative names
    • 30 kDa splicing factor SMNrp antibody
    • MGC106917 antibody
    • MGC112663 antibody
    • SMN related protein antibody
    • SMN-related protein antibody
    • smndc1 antibody
    • SMNR antibody
    • SPF30 antibody
    • SPF30_HUMAN antibody
    • Splicing factor 30, survival of motor neuron-related antibody
    • Survival motor neuron domain containing 1 antibody
    • Survival motor neuron domain containing protein 1 antibody
    • Survival motor neuron domain-containing protein 1 antibody
    • Survival of motor neuron related splicing factor 30 antibody
    • Survival of motor neuron-related-splicing factor 30 antibody
    see all

Images

  • Anti-SMNDC1 antibody (ab155021) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 32 kDa



    12% SDS PAGE
  • Immunofluorescent analysis of methanol-fixed HeLa cells labeling Survival motor neuron protein with ab155021 at 1/200 dilution. Lower panel is co-stained with Hoechst 33342.

References

ab155021 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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