Overview

  • Product nameAnti-SMOC1 antibody
    See all SMOC1 primary antibodies
  • Description
    Rabbit polyclonal to SMOC1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 283-313 of Human SMOC1 (NP_071420.1, NP_001030024.1).

  • Positive control
    • Mouse NIH3T3 cell line lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab116529 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG

Associated products

Applications

Our Abpromise guarantee covers the use of ab116529 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 48 kDa.

Target

  • FunctionPlays essential roles in both eye and limb development. Probale regulator of osteoblast differentiation.
  • Tissue specificityWidely expressed in many tissues with a strongest signal in ovary. No expression in spleen.
  • Involvement in diseaseDefects in SMOC1 are the cause of ophthalmoacromelic syndrome (OAS) [MIM:206920]. A rare disorder presenting with anophthalmia or microphthalmia and limb anomalies. Limb malformations include fused 4th and 5th metacarpals and short 5th finger in hands, and olygodactyly in foot (four toes). Most patients have bilateral anophthalmia/ microphthalmia, but unilateral abnormality is also noted. Other malformations are rare, but venous or vertebral anomaly was recognized each in single cases.
  • Sequence similaritiesContains 2 EF-hand domains.
    Contains 1 Kazal-like domain.
    Contains 2 thyroglobulin type-1 domains.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localizationSecreted > extracellular space > extracellular matrix > basement membrane. In or around the basement membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Secreted modular calcium-binding protein 1 antibody
    • SMOC-1 antibody
    • SMOC1 antibody
    • SMOC1_HUMAN antibody
    • SPARC-related modular calcium-binding protein 1 antibody
    see all

Anti-SMOC1 antibody images

  • Anti-SMOC1 antibody (ab116529) at 1/100 dilution + Mouse NIH3T3 cell line lysate at 35 µg

    Predicted band size : 48 kDa

References for Anti-SMOC1 antibody (ab116529)

This product has been referenced in:

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab116529.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"