Overview

  • Product name
  • Description
    Mouse polyclonal to Snf1lk
  • Host species
    Mouse
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-783 of Human Snf1lk (AAH38504.1).

  • Positive control
    • Snf1lk transfected 293T cell lysate; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab168263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 85 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function
    Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.
    Contains 1 protein kinase domain.
    Contains 1 UBA domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Nucleus. Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ.
  • Information by UniProt
  • Database links
  • Alternative names
    • KID2 antibody
    • MSK antibody
    • myocardial SNF1 like kinase antibody
    • QIK antibody
    • Qin-induced kinase antibody
    • Salt inducible kinase 1 antibody
    • Salt-inducible protein kinase 1 antibody
    • Serine threonine protein kinase SNF1 like kinase 1 antibody
    • Serine threonine protein kinase SNF1LK antibody
    • Serine/threonine-protein kinase SIK1 antibody
    • Serine/threonine-protein kinase SNF1-like kinase 1 antibody
    • Serine/threonine-protein kinase SNF1LK antibody
    • SIK-1 antibody
    • SIK1 antibody
    • SIK1_HUMAN antibody
    • SNF1 like kinase antibody
    see all

Images

  • All lanes : Anti-Snf1lk antibody (ab168263) at 1 µg/ml

    Lane 1 : Snf1lk transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Developed using the ECL technique.

    Predicted band size: 85 kDa

  • Immunofluorescence analysis of permeabilized, paraformaldehyde-fixed HeLa cells, labeling Snf1lk with ab168263 at 10 µg/ml.

References

ab168263 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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