Overview

  • Product name
  • Description
    Rabbit polyclonal to SNIP1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 41-323 of Human SNIP1 (Q8TAD8).

  • Positive control
    • Human 59T xenograft, Rat RT2 xenograft and Mouse Muscle tissues; 293T, A431, Jurkat and Raji whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab126194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 46 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis.
  • Tissue specificity
    Ubiquitous, with highest expression in heart and skeletal muscle.
  • Sequence similarities
    Contains 1 FHA domain.
  • Post-translational
    modifications
    Degraded by the proteasome upon binding to the SMAD1/OAZ1/PSMB4 complex.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FHA domain containing protein SNIP1 antibody
    • FHA domain-containing protein SNIP1 antibody
    • FLJ12553 antibody
    • PMRED antibody
    • Smad nuclear interacting protein (Smad nuclear interacting) antibody
    • smad nuclear interacting protein 1 antibody
    • Smad nuclear interacting protein antibody
    • Smad nuclear-interacting protein 1 antibody
    • SNIP1 (Smad nuclear interacting protein) antibody
    • SNIP1 antibody
    • SNIP1_HUMAN antibody
    • Splicing factor arginine/serine rich 4 (Pre mRNA splicing factor SRP75) antibody
    see all

Images

  • Anti-SNIP1 antibody (ab126194) at 1/5000 dilution + Jurkat whole cell lysate at 30 µg

    Predicted band size : 46 kDa
  • ab126194, at 1/500 dilution, staining SNIP1 in Paraffin-embedded Human 59T xenograft tissue by Immunohistochemistry.
  • ab126194, at 1/500 dilution, staining SNIP1 in Paraffin-embedded HumRat RT2 xenograft tissue by Immunohistochemistry.
  • ab126194, at 1/500 dilution, staining SNIP1 in Paraffin-embedded Mouse Muscle tissue by Immunohistochemistry.

References

ab126194 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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