Overview

  • Product name
  • Description
    Mouse polyclonal to SNIP1
  • Host species
    Mouse
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey
  • Immunogen

    Full length protein, corresponding to amino acids 1-396 of Human SNIP1 (AAH27040, UniProt ID: Q8TAD8).

  • Positive control
    • SNIP1-transfected 293T cell lysate. HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab169577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function
    Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis.
  • Tissue specificity
    Ubiquitous, with highest expression in heart and skeletal muscle.
  • Sequence similarities
    Contains 1 FHA domain.
  • Post-translational
    modifications
    Degraded by the proteasome upon binding to the SMAD1/OAZ1/PSMB4 complex.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FHA domain containing protein SNIP1 antibody
    • FHA domain-containing protein SNIP1 antibody
    • FLJ12553 antibody
    • PMRED antibody
    • Smad nuclear interacting protein (Smad nuclear interacting) antibody
    • smad nuclear interacting protein 1 antibody
    • Smad nuclear interacting protein antibody
    • Smad nuclear-interacting protein 1 antibody
    • SNIP1 (Smad nuclear interacting protein) antibody
    • SNIP1 antibody
    • SNIP1_HUMAN antibody
    • Splicing factor arginine/serine rich 4 (Pre mRNA splicing factor SRP75) antibody
    see all

Images

  • All lanes : Anti-SNIP1 antibody (ab169577) at 1 µg/ml

    Lane 1 : SNIP1-transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 15 µl per lane.

    Developed using the ECL technique.

    Predicted band size: 46 kDa

  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa cells, labeling SNIP1 using ab169577 at 10 µg/ml.

References

ab169577 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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