Overview

  • Product name
  • Description
    Rabbit polyclonal to SNRPB
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 71-120 (LRGENLVSMT VEGPPPKDTG IARVPLAGAA GGPGIGRAAG RGIPAGVPMP) of Human SNRPB, NP_003082.

  • Positive control
    • 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab85534 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
  • Sequence similarities
    Belongs to the snRNP SmB/SmN family.
  • Post-translational
    modifications
    Methylated. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • B polypeptide of Sm protein antibody
    • COD antibody
    • RSMB_HUMAN antibody
    • Sm B/B' antibody
    • Sm B/Sm B' antibody
    • Sm B/SmB' antibody
    • Sm protein B/B'' antibody
    • Sm-B/B'' antibody
    • Small nuclear ribonucleoprotein polypeptide B antibody
    • Small nuclear ribonucleoprotein polypeptide B/B' antibody
    • Small nuclear ribonucleoprotein polypeptides B and B' antibody
    • Small nuclear ribonucleoprotein polypeptides B and B1 antibody
    • Small nuclear ribonucleoprotein-associated proteins B and B'' antibody
    • SmB antibody
    • SmB/B'' antibody
    • SmB/Sm B' antibody
    • SmB/SmB' antibody
    • snRNP B antibody
    • snRNP-B antibody
    • snRNPB antibody
    • SNRPB antibody
    • SNRPB1 antibody
    see all

Images

  • Anti-SNRPB antibody (ab85534) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 24 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 38 kDa,60 kDa. We are unsure as to the identity of these extra bands.

References

ab85534 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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