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Rabbit polyclonal to SNRPD3
Mouse, Rat, HumanPredicted to work with:
Recombinant fragment, corresponding to amino acids 8-121 of Human SNRPD3 (P62318).
- RT4, U-251 MG and Human Tonsil cell lysates, Human small intestine tissue
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/50 - 1/200.
||1/100 - 1/250.
||Use at an assay dependent concentration.
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
Belongs to the snRNP core protein family.
Methylated on arginine residues by PRMT5 and PRMT7; methylation is required for assembly and biogenesis of snRNPs.
Arg-97 is dimethylated, probably to asymmetric dimethylarginine.
Information by UniProt
- Sm D3 antibody
- Sm-D3 antibody
- small nuclear ribonucleoprotein D3 polypeptide 18kDa antibody
Immunocytochemistry - Anti-SNRPD3 antibody (ab121129)
Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but excluded from the nucleoli.
Western blot - Anti-SNRPD3 antibody (ab121129)
All lanes : Anti-SNRPD3 antibody (ab121129) at 1/250 dilution
Lane 1 : RT4 cell lysate
Lane 2 : U-251 MG cell lysate
Lane 3 : Human Plasma lysate
Lane 4 : Human Liver lysate
Lane 5 : Human Tonsil lysate
Developed using the ECL technique.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SNRPD3 antibody (ab121129)
ab121129 staining SNRPD3 in Paraffin-emebedded Human small intestine tissue by Immunohistochemistry.
Note: strong nuclear positivity in glandular cells.
has not yet been referenced specifically in any publications.
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