Overview

  • Product nameAnti-SNRPD3 antibody
    See all SNRPD3 primary antibodies
  • Description
    Rabbit polyclonal to SNRPD3
  • Tested applicationsSuitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Xenopus laevis
  • Immunogen

    Recombinant fragment, corresponding to amino acids 8-121 of Human SNRPD3 (P62318).

  • Positive control
    • RT4, U-251 MG and Human Tonsil cell lysates, Human small intestine tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.
WB 1/100 - 1/250.
ICC/IF Use at an assay dependent concentration.

Target

  • FunctionAppears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
  • Sequence similaritiesBelongs to the snRNP core protein family.
  • Post-translational
    modifications
    Methylated on arginine residues by PRMT5 and PRMT7; methylation is required for assembly and biogenesis of snRNPs.
    Arg-97 is dimethylated, probably to asymmetric dimethylarginine.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Sm D3 antibody
    • Sm-D3 antibody
    • small nuclear ribonucleoprotein D3 polypeptide 18kDa antibody
    • Small nuclear ribonucleoprotein Sm D3 antibody
    • SmD3 antibody
    • SMD3_HUMAN antibody
    • snRNP core protein D3 antibody
    • SNRPD3 antibody
    see all

Anti-SNRPD3 antibody images

  • Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but excluded from the nucleoli.
  • All lanes : Anti-SNRPD3 antibody (ab121129) at 1/250 dilution

    Lane 1 : RT4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique
  • ab121129 staining SNRPD3 in Paraffin-emebedded Human small intestine tissue by Immunohistochemistry. Note: strong nuclear positivity in glandular cells.

References for Anti-SNRPD3 antibody (ab121129)

ab121129 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"