General notesab94333 is a 293T cell transfected lysate in which Human SNX10 has been transiently over-expressed using a pCMV-SNX10 plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more detail about how the transfected lysate was prepared view preparation notes
BackgroundFunction: May be involved in several stages of intracellular trafficking (By similarity). May play a role in endosome homeostasis. Overexpression causes formation of huge vacuoles.
Similarity: Belongs to the sorting nexin family.
Contains 1 PX (phox homology) domain.
Domain: The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.