Overview

  • Product name
  • Description
    Goat polyclonal to SNX16
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide (

    ATPYVPVPMPIGN-C

    ) corresponding to N terminal amino acids 2-14 of Human SNX16.

  • Positive control
    • Human breast, placenta and tonsil tissues; Daudi cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.05 - 0.2 µg/ml. Predicted molecular weight: 39 kDa.
ELISA 1/64000.
IHC-P Use a concentration of 3.75 µg/ml.

Target

  • Function
    May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
  • Tissue specificity
    Detected in placenta, lung, liver,heart and pancreas.
  • Sequence similarities
    Belongs to the sorting nexin family.
    Contains 1 PX (phox homology) domain.
  • Domain
    The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.
  • Cellular localization
    Early endosome membrane. Late endosome membrane. Cytoplasm. Lysosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp666H147 antibody
    • OTTHUMP00000227313 antibody
    • OTTHUMP00000227314 antibody
    • SNX16 antibody
    • SNX16_HUMAN antibody
    • Sorting nexin-16 antibody
    see all

Images

  • Anti-SNX16 antibody (ab113885) at 0.05 µg/ml + Daudi lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 39 kDa


    Exposure time : 1 hour
  • ab113885, at 3.75 µg/ml, staining SNX16 in formalin fixed, paraffin embedded Human breast tissue by Immunohistochemistry.
  • ab113885, at 3.75 µg/ml, staining SNX16 in formalin fixed, paraffin embedded Human placenta tissue by Immunohistochemistry.
  • ab113885, at 3.75 µg/ml, staining SNX16 in formalin fixed, paraffin embedded Human tonsil tissue by Immunohistochemistry.

References

ab113885 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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