The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 53 kDa (predicted molecular weight: 53 kDa).
RelevanceThe SNX17 gene encodes a member of the sorting nexin family. Members of this family are involved in intracellular trafficking, and contain a phox (PX) domain, which is a phosphoinositide binding domain. The protein contains a B41 domain, but does not contain a coiled coil region, like some family members. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin.
Cellular localizationCytoplasm. Note=Associated with early endosomes.