Overview

  • Product nameAnti-SNX18 antibody
    See all SNX18 primary antibodies
  • Description
    Rabbit polyclonal to SNX18
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Cow
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 107-156 (LLQPQQAPPP STFQPPGAGF PYGGGALQPS PQQLYGGYQA SQGSDDDWDD) of Human SNX18 (NP_443102)

  • Positive control
    • 721_B cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab99035 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 69 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
  • Sequence similaritiesBelongs to the sorting nexin family.
    Contains 1 BAR domain.
    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
  • DomainThe PX domain mediates interaction with membranes enriched in phosphatidylinositol-4,5-bisphosphate.
  • Cellular localizationEndomembrane system. Endosome membrane. Cell membrane. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ11997 antibody
    • FLJ32560 antibody
    • FLJ61062 antibody
    • MGC150827 antibody
    • MGC150829 antibody
    • SH3 and PX domain containing protein 3B antibody
    • SH3 and PX domain-containing protein 3B antibody
    • SH3PX2 antibody
    • SH3PXD3B antibody
    • SNAG 1 antibody
    • SNAG1 antibody
    • SNX18 antibody
    • SNX18_HUMAN antibody
    • Sorting nexin 18 antibody
    • Sorting nexin associated golgi protein 1 antibody
    • Sorting nexin-18 antibody
    • Sorting nexin-associated Golgi protein 1 antibody
    see all

Anti-SNX18 antibody images

  • Anti-SNX18 antibody (ab99035) at 1 µg/ml + 721_B cell lysate at 10 µg

    Predicted band size : 69 kDa

References for Anti-SNX18 antibody (ab99035)

ab99035 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"