Overview

  • Product name
  • Description
    Rabbit polyclonal to Snx6
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant Human Snx6 protein.

  • Positive control
    • HL60 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab135761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 47 kDa.

Target

  • Relevance
    Snx6 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.
  • Cellular localization
    Endosomes
  • Database links
  • Alternative names
    • Sorting Nexin 6 antibody
    • TFAF2 antibody
    • TRAF4 Associated Factor 2 antibody

Images

  • Anti-Snx6 antibody (ab135761) at 1/100 dilution + HL60 cell lysate at 35 µg

    Predicted band size : 47 kDa

References

ab135761 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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