Overview

  • Product nameAnti-SOCS4 antibody
    See all SOCS4 primary antibodies
  • Description
    Rabbit polyclonal to SOCS4
  • Tested applicationsSuitable for: WB, IP, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide KLH conjugated, derived from the C-terminus of Human SOCS4 (NP_543143.1).

  • Positive control
    • Human Adrenal tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferpH: 7.40
    Preservative: 0.05% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab118530 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 51 kDa.
IP Use 0.3-0.5µg for 106 cells.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionSOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 1 SH2 domain.
    Contains 1 SOCS box domain.
  • DomainThe SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
  • Information by UniProt
  • Database links
  • Alternative names
    • CIS4 antibody
    • Cish4 antibody
    • Cytokine inducible SH2 protein 4 antibody
    • DKFZp686J1568 antibody
    • HSPC060 antibody
    • SH2 domain containing SOCS box protein antibody
    • SOCS-4 antibody
    • SOCS-7 antibody
    • SOCS4 antibody
    • SOCS4_HUMAN antibody
    • SOCS6 antibody
    • SOCS7 antibody
    • SSI4 antibody
    • STAI4 antibody
    • STAT induced STAT inhibitor 4 antibody
    • STAT4 antibody
    • STATI4 antibody
    • Suppressor of cytokine signaling 4 antibody
    • Suppressor of cytokine signaling 7 antibody
    see all

Anti-SOCS4 antibody images

  • Human Adrenal tissue (formalin-fixed, paraffin-embedded) stained with ab118530 at 10 µg/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-SOCS4 antibody (ab118530)

ab118530 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"