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Storage instructions Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 40% Glycerol, PBS, pH 7
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 51 kDa.
1/100 - 1/200.
Function SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Pathway Protein modification; protein ubiquitination.
Sequence similarities Contains 1 SH2 domain. Contains 1 SOCS box domain.
Domain The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Information by UniProt
Cytokine inducible SH2 protein 4 antibody
Anti-SOCS4 antibody images
Western blot - SOCS4 antibody (ab97285)
Anti-SOCS4 antibody (ab97285) at 1/200 dilution + HeLa S3 whole cell lysate at 30 µg Predicted band size : 51 kDa
Immunocytochemistry/ Immunofluorescence - SOCS4 antibody (ab97285)
Immunofluorescence analysis of SOCS4 in paraformaldehyde fixed HeLa, using ab97285 at a 1/200 dilution. The lower image was co-stained with Hoechst 33342.
References for Anti-SOCS4 antibody (ab97285)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"