Overview

  • Product nameAnti-SOCS6 antibody
    See all SOCS6 primary antibodies
  • Description
    Rabbit polyclonal to SOCS6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human recombinant SOCS6 protein fused to an N-terminal tag (expressed in E. coli)

Properties

Applications

Our Abpromise guarantee covers the use of ab13950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Predicted molecular weight: 60 kDa. This antibody has only been tested against over-expressing cell lines and against the recombinant fusion protein used as immunogen.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    • PathwayProtein modification; protein ubiquitination.
    • Sequence similaritiesContains 1 SH2 domain.
      Contains 1 SOCS box domain.
    • DomainThe SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
    • Information by UniProt
    • Database links
    • Alternative names
      • CIS-4 antibody
      • CIS4 antibody
      • Cish4 antibody
      • Cytokine inducible SH2 protein 4 antibody
      • Cytokine-inducible SH2 protein 4 antibody
      • HSPC060 antibody
      • SOCS-4 antibody
      • SOCS-6 antibody
      • SOCS4 antibody
      • Socs6 antibody
      • SOCS6_HUMAN antibody
      • SSI4 antibody
      • STAI4 antibody
      • STAT induced STAT inhibitor 4 antibody
      • STAT4 antibody
      • STATI4 antibody
      • Suppressor of cytokine signaling 4 antibody
      • Suppressor of cytokine signaling 6 antibody
      see all

    Anti-SOCS6 antibody images

    • All lanes : Anti-SOCS6 antibody (ab13950) at 1/500 dilution

      Lane 1 : Untransfected 293T cells
      Lane 2 : 293T cells transfected with empty vector
      Lane 3 : 293T cells transfected with vector expressing SOCS-6 protein


      Predicted band size : 60 kDa

    References for Anti-SOCS6 antibody (ab13950)

    ab13950 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"