Overview

  • Product nameAnti-SOCS6 antibody, prediluted
    See all SOCS6 primary antibodies
  • Description
    Rabbit polyclonal to SOCS6, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to C terminal of human SOCS6 protein.

  • Positive control
    • A431 and HeLa cells. Placenta.

Properties

Applications

Our Abpromise guarantee covers the use of ab53211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready-to-use for 30 min at RT.

    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM
    citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    • PathwayProtein modification; protein ubiquitination.
    • Sequence similaritiesContains 1 SH2 domain.
      Contains 1 SOCS box domain.
    • DomainThe SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
    • Information by UniProt
    • Database links
    • Alternative names
      • CIS-4 antibody
      • CIS4 antibody
      • Cish4 antibody
      • Cytokine inducible SH2 protein 4 antibody
      • Cytokine-inducible SH2 protein 4 antibody
      • HSPC060 antibody
      • SOCS-4 antibody
      • SOCS-6 antibody
      • SOCS4 antibody
      • Socs6 antibody
      • SOCS6_HUMAN antibody
      • SSI4 antibody
      • STAI4 antibody
      • STAT induced STAT inhibitor 4 antibody
      • STAT4 antibody
      • STATI4 antibody
      • Suppressor of cytokine signaling 4 antibody
      • Suppressor of cytokine signaling 6 antibody
      see all

    References for Anti-SOCS6 antibody, prediluted (ab53211)

    This product has been referenced in:
    • Letellier E  et al. Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer. Br J Cancer 111:726-35 (2014). IHC-P ; Human . Read more (PubMed: 25025962) »

    See 1 Publication for this product

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