• Product nameAnti-SOD2/MnSOD antibody
    See all SOD2/MnSOD primary antibodies
  • Description
    Goat polyclonal to SOD2/MnSOD
  • Specificityab118340 is expected to recognize both reported isoforms (NP_000627.2; NP_001019637.1). The immunizing peptide represents the acetylation site including K122 according to isoform A.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to Human SOD2/MnSOD aa 119-130 (internal sequence) (Cysteine residue).


    Database link: P04179

  • Positive control
    • Mouse and Rat spinal cord and Human Brain (cerebellum) lysates.


Associated products


Our Abpromise guarantee covers the use of ab118340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:64,000.

WB Use a concentration of 0.01 - 0.1 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 25 kDa).


  • FunctionDestroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  • Involvement in diseaseGenetic variation in SOD2 is associated with susceptibility to microvascular complications of diabetes type 6 (MVCD6) [MIM:612634]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.
  • Sequence similaritiesBelongs to the iron/manganese superoxide dismutase family.
  • Post-translational
    Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity.
  • Cellular localizationMitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Indophenoloxidase B antibody
    • IPO B antibody
    • IPOB antibody
    • Manganese containing superoxide dismutase antibody
    • Manganese SOD antibody
    • Manganese superoxide dismutase antibody
    • Mangano superoxide dismutase antibody
    • Mn SOD antibody
    • Mn superoxide dismutase antibody
    • MNSOD antibody
    • MVCD6 antibody
    • SOD 2 antibody
    • SOD2 antibody
    • SODM_HUMAN antibody
    • Superoxide dismutase [Mn] mitochondrial antibody
    • Superoxide dismutase [Mn], mitochondrial antibody
    • Superoxide dismutase 2 mitochondrial antibody
    see all

Anti-SOD2/MnSOD antibody images

  • All lanes : Anti-SOD2/MnSOD antibody (ab118340)

    Lane 1 : Human Cerebellum lysate
    Lane 2 : Mouse Brain lysate
    Lane 3 : Rat Brain lysate
    Lane 4 : Pig Brain lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size : 25 kDa
  • All lanes : Anti-SOD2/MnSOD antibody (ab118340)

    Lane 1 : HeLa cell lysate
    Lane 2 : HepG2
    Lane 3 : HEK293
    Lane 4 : NIH3T3

    Lysates/proteins at 35 µg per lane.

    Predicted band size : 25 kDa
  • Anti-SOD2/MnSOD antibody (ab118340) at 0.1 µg/ml (incubation time: 1 hour) + Mouse Spinal Cord lysate in RIPA buffer at 35 µg
    developed using the ECL technique

    Predicted band size : 25 kDa

References for Anti-SOD2/MnSOD antibody (ab118340)

ab118340 has not yet been referenced specifically in any publications.

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