• Product name
  • Description
    Goat polyclonal to SOD2/MnSOD
  • Specificity
    ab118340 is expected to recognize both reported isoforms (NP_000627.2; NP_001019637.1). The immunizing peptide represents the acetylation site including K122 according to isoform A.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to Human SOD2/MnSOD aa 119-130 (internal sequence) (Cysteine residue).


    Database link: P04179

  • Positive control
    • Mouse and Rat spinal cord and Human Brain (cerebellum) lysates.



Our Abpromise guarantee covers the use of ab118340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:64,000.

WB Use a concentration of 0.01 - 0.1 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 25 kDa).


  • Function
    Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  • Involvement in disease
    Genetic variation in SOD2 is associated with susceptibility to microvascular complications of diabetes type 6 (MVCD6) [MIM:612634]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.
  • Sequence similarities
    Belongs to the iron/manganese superoxide dismutase family.
  • Post-translational
    Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity.
  • Cellular localization
    Mitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Indophenoloxidase B antibody
    • IPO B antibody
    • IPOB antibody
    • Manganese containing superoxide dismutase antibody
    • Manganese SOD antibody
    • Manganese superoxide dismutase antibody
    • Mangano superoxide dismutase antibody
    • Mn SOD antibody
    • Mn superoxide dismutase antibody
    • MNSOD antibody
    • MVCD6 antibody
    • SOD 2 antibody
    • SOD2 antibody
    • SODM_HUMAN antibody
    • Superoxide dismutase [Mn] mitochondrial antibody
    • Superoxide dismutase [Mn], mitochondrial antibody
    • Superoxide dismutase 2 mitochondrial antibody
    see all

Anti-SOD2/MnSOD antibody images

  • All lanes : Anti-SOD2/MnSOD antibody (ab118340)

    Lane 1 : Human Cerebellum lysate
    Lane 2 : Mouse Brain lysate
    Lane 3 : Rat Brain lysate
    Lane 4 : Pig Brain lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size : 25 kDa
  • All lanes : Anti-SOD2/MnSOD antibody (ab118340)

    Lane 1 : HeLa cell lysate
    Lane 2 : HepG2
    Lane 3 : HEK293
    Lane 4 : NIH3T3

    Lysates/proteins at 35 µg per lane.

    Predicted band size : 25 kDa
  • Anti-SOD2/MnSOD antibody (ab118340) at 0.1 µg/ml (incubation time: 1 hour) + Mouse Spinal Cord lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 25 kDa

References for Anti-SOD2/MnSOD antibody (ab118340)

ab118340 has not yet been referenced specifically in any publications.

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