Anti-Sodium / Hydrogen Exchanger 1 antibody [4E9] (ab24018)

Overview

  • Product nameAnti-Sodium / Hydrogen Exchanger 1 antibody [4E9]
    See all Sodium / Hydrogen Exchanger 1 primary antibodies
  • Description
    Mouse monoclonal [4E9] to Sodium / Hydrogen Exchanger 1
  • SpecificityNa+/H+ exchanger, isoform NHE1.
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: IHC-Fr,IHC-P or IP
  • Species reactivity
    Reacts with: Human, Pig
  • Immunogen

    Fusion protein (Pig). MBP fusion protein containing the entire C-terminal, hydrophylic domain of porcine NHE1

Properties

Applications

Our Abpromise guarantee covers the use of ab24018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 91 kDa.
  • Application notesIs unsuitable for IHC-Fr,IHC-P or IP.
  • Target

    • FunctionInvolved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
    • Tissue specificityKidney and intestine.
    • Sequence similaritiesBelongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
      O-glycosylated.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • amiloride-sensitive antibody
      • APNH antibody
      • APNH1 antibody
      • FLJ42224 antibody
      • Na Li countertransporter antibody
      • Na(+)/H(+) antiporter antibody
      • Na(+)/H(+) exchanger 1 antibody
      • Na+ H+ antiporter amiloride-sensitive antibody
      • Na+ H+ antiporter antibody
      • Na+ H+ exchanger 1 antibody
      • NHE-1 antibody
      • NHE1 antibody
      • OTTHUMP00000004468 antibody
      • SL9A1_HUMAN antibody
      • SLC9A1 antibody
      • Sodium hydrogen exchanger 1 antibody
      • Sodium/hydrogen exchanger 1 antibody
      • solute carrier family 9 antibody
      • Solute carrier family 9 member 1 antibody
      • Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive antibody
      • Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1 antibody
      • Solute carrier family 9 subfamily A member 1 antibody
      see all

    References for Anti-Sodium / Hydrogen Exchanger 1 antibody [4E9] (ab24018)

    This product has been referenced in:
    • Busco G  et al. NHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial space. FASEB J 24:3903-15 (2010). WB ; Human . Read more (PubMed: 20547664) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"