The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 91 kDa.
Application notesIs unsuitable for IHC-Fr,IHC-P or IP.
FunctionInvolved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Tissue specificityKidney and intestine.
Sequence similaritiesBelongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Post-translational modificationsPhosphorylated upon DNA damage, probably by ATM or ATR. O-glycosylated.