Anti-Sodium / Hydrogen Exchanger 1 antibody (ab181479)

Overview

  • Product name
    Anti-Sodium / Hydrogen Exchanger 1 antibody
    See all Sodium / Hydrogen Exchanger 1 primary antibodies
  • Description
    Goat polyclonal to Sodium / Hydrogen Exchanger 1
  • Host species
    Goat
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow, Pig
  • Immunogen

    Synthetic peptide corresponding to Human Sodium/ Hydrogen Exchanger 1 aa 670-683 (internal sequence) (Cysteine residue). NP_003038.2
    Sequence:

    RQKARQLEQKINNY


    Database link: P19634

  • Positive control
    • Human kidney lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab181479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 80 kDa (predicted molecular weight: 91 kDa).

Target

  • Function
    Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
  • Tissue specificity
    Kidney and intestine.
  • Sequence similarities
    Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
    O-glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • amiloride-sensitive antibody
    • APNH antibody
    • APNH1 antibody
    • FLJ42224 antibody
    • Na Li countertransporter antibody
    • Na(+)/H(+) antiporter antibody
    • Na(+)/H(+) exchanger 1 antibody
    • Na+ H+ antiporter amiloride-sensitive antibody
    • Na+ H+ antiporter antibody
    • Na+ H+ exchanger 1 antibody
    • NHE-1 antibody
    • NHE1 antibody
    • OTTHUMP00000004468 antibody
    • SL9A1_HUMAN antibody
    • SLC9A1 antibody
    • Sodium hydrogen exchanger 1 antibody
    • Sodium/hydrogen exchanger 1 antibody
    • solute carrier family 9 antibody
    • Solute carrier family 9 member 1 antibody
    • Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive antibody
    • Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1 antibody
    • Solute carrier family 9 subfamily A member 1 antibody
    see all

Images

  • Anti-Sodium / Hydrogen Exchanger 1 antibody (ab181479) at 1 µg/ml + Human kidney lysate in RIPA buffer at 35 µg

    Developed using the ECL technique.

    Predicted band size: 91 kDa
    Observed band size: 80 kDa (why is the actual band size different from the predicted?)



    Primary incubation was 1 hour.

References

ab181479 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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