Anti-Sodium / Hydrogen Exchanger 1 antibody (ab67314)


  • Product nameAnti-Sodium / Hydrogen Exchanger 1 antibody
    See all Sodium / Hydrogen Exchanger 1 primary antibodies
  • Description
    Rabbit polyclonal to Sodium / Hydrogen Exchanger 1
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-FoFr, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 17 amino acid synthetic peptide from near the center of Human Sodium/ Hydrogen Exchanger 1.

  • Positive control
    • MOLT4 cell lysate. Human brain tissue.



Our Abpromise guarantee covers the use of ab67314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 20817726
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa).
IHC-FoFr Use at an assay dependent concentration. PubMed: 20712402
IHC-P Use at an assay dependent concentration.


  • FunctionInvolved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
  • Tissue specificityKidney and intestine.
  • Sequence similaritiesBelongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • Post-translational
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • amiloride-sensitive antibody
    • APNH antibody
    • APNH1 antibody
    • FLJ42224 antibody
    • Na Li countertransporter antibody
    • Na(+)/H(+) antiporter antibody
    • Na(+)/H(+) exchanger 1 antibody
    • Na+ H+ antiporter amiloride-sensitive antibody
    • Na+ H+ antiporter antibody
    • Na+ H+ exchanger 1 antibody
    • NHE-1 antibody
    • NHE1 antibody
    • OTTHUMP00000004468 antibody
    • SL9A1_HUMAN antibody
    • SLC9A1 antibody
    • Sodium hydrogen exchanger 1 antibody
    • Sodium/hydrogen exchanger 1 antibody
    • solute carrier family 9 antibody
    • Solute carrier family 9 member 1 antibody
    • Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive antibody
    • Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1 antibody
    • Solute carrier family 9 subfamily A member 1 antibody
    see all

Anti-Sodium / Hydrogen Exchanger 1 antibody images

  • Lane 1 : Anti-Sodium / Hydrogen Exchanger 1 antibody (ab67314) at 1 µg/ml
    Lane 2 : Anti-Sodium / Hydrogen Exchanger 1 antibody (ab67314) at 2 µg/ml

    Lane 1 : MOLT4 cell lysate
    Lane 2 : MOLT4 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size : 91 kDa
    Observed band size : 91 kDa
    Additional bands at : 48 kDa (possible isoform).
  • Immunofluorescence of Nhe-1 in Human Brain cells using ab67314 at 20 ug/ml.

References for Anti-Sodium / Hydrogen Exchanger 1 antibody (ab67314)

This product has been referenced in:
  • Cengiz P  et al. Inhibition of Na+/H+ exchanger isoform 1 is neuroprotective in neonatal hypoxic ischemic brain injury. Antioxid Redox Signal 14:1803-13 (2011). WB, IHC-FoFr ; Mouse . Read more (PubMed: 20712402) »
  • Magalhaes MA  et al. Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol 195:903-20 (2011). Read more (PubMed: 22105349) »

See all 3 Publications for this product

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