Overview

  • Product name
    Anti-Sodium / Hydrogen Exchanger 3 antibody
    See all Sodium / Hydrogen Exchanger 3 primary antibodies
  • Description
    Rabbit polyclonal to Sodium / Hydrogen Exchanger 3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    DSFLQADGPEEQLQPASPESTHM

    , corresponding to C terminal amino acids 809-831 of Rat Sodium/ Hydrogen Exchanger 3 (NP_036786).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • Rat kidney tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab95299 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 84 kDa (predicted molecular weight: 93 kDa).

Target

  • Function
    Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
  • Sequence similarities
    Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • Post-translational
    modifications
    Phosphorylated by PKA, which inhibits activity.
  • Cellular localization
    Membrane. In intestinal epithelial cells, localizes to the ileal brush border.
  • Information by UniProt
  • Database links
    • Alternative names
      • MGC126718 antibody
      • MGC126720 antibody
      • Na(+)/H(+) exchanger 3 antibody
      • NHE 3 antibody
      • NHE-3 antibody
      • NHE3 antibody
      • SL9A3_HUMAN antibody
      • SLC9A 3 antibody
      • Slc9a3 antibody
      • Sodium/hydrogen exchanger 3 antibody
      • Sodium/hydrogen exchanger, apical epithelial antibody
      • Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 antibody
      • Solute carrier family 9 (sodium/hydrogen exchanger), member 3 antibody
      • Solute carrier family 9 member 3 antibody
      see all

    Images

    • Western blot - Anti-Sodium / Hydrogen Exchanger 3 antibody (ab95299)
      Western blot - Anti-Sodium / Hydrogen Exchanger 3 antibody (ab95299)
      Western blot detection of Sodium / Hydrogen Exchanger 3 in Rat kidney tissues using ab95299 at 1:1000 dilution.

    References

    This product has been referenced in:
    • Wang YY  et al. Loss of SLC9A3 decreases CFTR protein and causes obstructed azoospermia in mice. PLoS Genet 13:e1006715 (2017). IHC-P ; Mouse . Read more (PubMed: 28384194) »

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