Overview

  • Product nameAnti-Solo antibody
    See all Solo primary antibodies
  • Description
    Rabbit polyclonal to Solo
  • Tested applicationsSuitable for: ICC/IF, WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 15 amino acid synthetic peptide from near the C terminus of Human Solo (NP_835224).

  • Positive control
    • Rat brain tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105345 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 79 kDa.
ICC Use a concentration of 5 µg/ml.

Target

  • FunctionMay act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
  • Tissue specificityBroad expression. High expression in thalamus and brain. Significantly expressed in vasculature.
  • Sequence similaritiesBelongs to the SOLO family.
    Contains 1 CRAL-TRIO domain.
    Contains 3 spectrin repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • huntingtin interacting protein like protein antibody
    • Huntingtin-interacting protein-like protein antibody
    • Protein Solo antibody
    • SEC14 and spectrin domains 1 antibody
    • SEC14 domain and spectrin repeat-containing protein 1 antibody
    • SESD1_HUMAN antibody
    • sestd1 antibody
    • SOLO antibody
    see all

Anti-Solo antibody images

  • All lanes : Anti-Solo antibody (ab105345) at 1 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat brain tissue lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 79 kDa
  • Immunohistochemistry of Solo in human brain tissue with ab105345 at 5 µg/ml.
  • Immunofluorescence of SESTD1 in Human Brain cells using ab105345 at 20 ug/ml.

References for Anti-Solo antibody (ab105345)

ab105345 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105345.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"