Recombinant
RabMAb

Anti-Solo antibody [EPR13772] (ab181228)

Overview

  • Product name
    Anti-Solo antibody [EPR13772]
    See all Solo primary antibodies
  • Description
    Rabbit monoclonal [EPR13772] to Solo
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment within Human Solo aa 150-300. The exact sequence is proprietary.
    Database link: Q86VW0

  • Positive control
    • Human fetal brain lysate; HepG2 cell lysate; Human kidney and liver tissues.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab181228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/20000. Detects a band of approximately 79 kDa (predicted molecular weight: 79 kDa).
IHC-P 1/50 - 1/100.

Target

  • Function
    May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
  • Tissue specificity
    Broad expression. High expression in thalamus and brain. Significantly expressed in vasculature.
  • Sequence similarities
    Belongs to the SOLO family.
    Contains 1 CRAL-TRIO domain.
    Contains 3 spectrin repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • huntingtin interacting protein like protein antibody
    • Huntingtin-interacting protein-like protein antibody
    • Protein Solo antibody
    • SEC14 and spectrin domains 1 antibody
    • SEC14 domain and spectrin repeat-containing protein 1 antibody
    • SESD1_HUMAN antibody
    • sestd1 antibody
    • SOLO antibody
    see all

Images

  • Anti-Solo antibody [EPR13772] (ab181228) at 1/5000 dilution + HepG2 cell lysate at 20 µg

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

    Predicted band size : 79 kDa
  • Immunohistochemical analysis of paraffin-embedded Human liver tissue labeling Solo with ab181228 at 1/100 dilution followed by pre-diluted HRP-conjugated secondary antibody and counter-stained with Hematoxylin.

  • Anti-Solo antibody [EPR13772] (ab181228) at 1/20000 dilution + Human fetal brain lysate at 20 µg

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

    Predicted band size : 79 kDa
  • Immunohistochemical analysis of paraffin-embedded Human kidney tissue labeling Solo with ab181228 at 1/100 dilution followed by pre-diluted HRP-conjugated secondary antibody and counter-stained with Hematoxylin.

References

ab181228 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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