The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).
RelevanceSolute carrier family 22 member 18 may act as a transporter of organic cations based on a proton efflux antiport mechanism. It may also play a role in the transport of chloroquine and quinidine-related compounds in kidney.
Cellular localizationApical cell membrane; Multi-pass membrane protein (Potential). Note: Localized at the apical membrane surface of renal proximal tubules.