Anti-Somatostatin Receptor 1 antibody (ab100881)

Overview

  • Product nameAnti-Somatostatin Receptor 1 antibody
    See all Somatostatin Receptor 1 primary antibodies
  • Description
    Rabbit polyclonal to Somatostatin Receptor 1
  • Tested applicationsSuitable for: WB, IHC-P, ICC, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Horse, Cow, Dog, Human, Pig
  • Immunogen

    Synthetic peptide:

    ESGGVFRNGTCASRISTL

    , corresponding to C terminal amino acids 374-391 of Mouse and Rat Somatostatin Receptor 1

Properties

Applications

Our Abpromise guarantee covers the use of ab100881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000. Predicted molecular weight: 43 kDa.
IHC-P 1/2000.
ICC 1/5000.
ICC/IF Use at an assay dependent concentration.

Target

  • FunctionReceptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
  • Tissue specificityFetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • G-protein coupled receptor antibody
    • Somatostatin R1 antibody
    • Somatostatin receptor 1 antibody
    • Somatostatin receptor isoform 1 antibody
    • Somatostatin receptor type 1 antibody
    • SRIF 2 antibody
    • SRIF-2 antibody
    • SRIF2 antibody
    • SS-1-R antibody
    • SS1 R antibody
    • SS1-R antibody
    • SS1R antibody
    • SSR1_HUMAN antibody
    • SSTR 1 antibody
    • Sstr1 antibody
    see all

Anti-Somatostatin Receptor 1 antibody images

  • ab100881 at 1/5000 showing dual labeling of anti-sst1 (green) and somatostatin (red). Anti-Sst1 shows sst1 in neuronal terminals co-localized with somatostatin
  • ab100881 showing anti-Sst1 depicts sst1 as a presynaptic receptor in the superficial layers of the spinal cord dorsal horn

References for Anti-Somatostatin Receptor 1 antibody (ab100881)

ab100881 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Blocking step nomal goat serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 20°C
Antigen retrieval step None
Sample Mouse Tissue sections (Brain)
Specification Brain
Permeabilization Yes - 0,3% Triton X100
Fixative Paraformaldehyde
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Submitted Nov 13 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"