Our Abpromise guarantee covers the use of ab28618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/2500.
ICC 1/5000.
WB 1/5000. Detects a band of approximately 54-63 kDa.
ICC/IF Use a concentration of 5 µg/ml.


  • FunctionReceptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
  • Tissue specificityAdult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • SSTR5 antibody
    • Somatostatin receptor subtype 5 antibody
    • Somatostatin receptor type 5 antibody
    • SS 5R antibody
    • SS-5-R antibody
    • SS5 R antibody
    • SS5-R antibody
    • SS5R antibody
    • SSR5_HUMAN antibody
    • SST R5 antibody
    • SSTR 5 antibody
    • Sstr5 antibody
    see all

Anti-Somatostatin Receptor 5 antibody images

  • Anti-Somatostatin Receptor 5 antibody (ab28618) at 1 µg/ml + Brain: pituitary gland (Human) Whole Cell Lysate - adult normal tissue (ab29749) at 10 µg

    Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Observed band size : 42 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 15 kDa,20 kDa,73 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 8 minutes
    Somatostatin Receptor 5 contains a number of potential glycosylation sites (SwissProt) which may explain its migration at a higher molecular weight than predicted. Abcam welcomes customer feedback and would appreciate any comments regarding this product and the data presented above.
  • ICC/IF image of ab28618 stained MCF7 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab28618, 5µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

References for Anti-Somatostatin Receptor 5 antibody (ab28618)

This product has been referenced in:
  • Gonzalez B  et al. Cytoplasmic expression of SSTR2 and 5 by immunohistochemistry and by RT/PCR is not associated with the pharmacological response to octreotide. Endocrinol Nutr 61:523-30 (2014). Read more (PubMed: 25008035) »
  • Ramírez C  et al. Expression of Ki-67, PTTG1, FGFR4, and SSTR 2, 3, and 5 in nonfunctioning pituitary adenomas: a high throughput TMA, immunohistochemical study. J Clin Endocrinol Metab 97:1745-51 (2012). IHC-P ; Human . Read more (PubMed: 22419713) »

See all 5 Publications for this product

Product Wall

Thank you vary much for your patience while I contacted the products originator. According to the original researcher (and author of the paper that I provided), "most GPCRs are N-glycosylated proteins which accounts for 10 to 30 kDa higher molecular w...

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Thank you for your enquiry. In Charlotte's absence I am handling her enquiries. According to the original researcher (and author of the paper that Charlotte provided you with), "most GPCRs are N-glycosylated proteins which accounts for 10 to 30 kDa...

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