Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA).
Use at an assay dependent concentration. Preliminary experiments gave an approx 35kDa band in Human, Mouse and Rat Heart lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 250kDa according to NP_115571.1. The 35kDa band was successfully blocked by incubation with the immunizing peptide.
FunctionRepresses hepatitis B virus (HBV) core promoter activity and transcription of HBV genes and production of HBV virions. Binds to the consensus DNA sequence: 5'-GA[GT]AN[CG][AG]CC-3'. Might protect cells from apoptosis. Might be involved in pre-mRNA splicing.
Tissue specificityWidely expressed, with the higher expression seen in leukocyte and heart.