Anti-Sorbitol Dehydrogenase antibody (ab113874)

Overview

  • Product nameAnti-Sorbitol Dehydrogenase antibody
    See all Sorbitol Dehydrogenase primary antibodies
  • Description
    Rabbit polyclonal to Sorbitol Dehydrogenase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Rabbit, Horse, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide (ASGTVEKVGS SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA) corresponding to a region within N terminal amino acids 72-121 of Human Sorbitol Dehydrogenase (NP_003095).

  • Positive control
    • HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionConverts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm.
  • Tissue specificityExpressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level).
  • Sequence similaritiesBelongs to the zinc-containing alcohol dehydrogenase family.
  • Cellular localizationMitochondrion membrane. Cell projection > cilium > flagellum. Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
  • Information by UniProt
  • Database links
  • Alternative names
    • DHSO_HUMAN antibody
    • L iditol 2 dehydrogenase antibody
    • L-iditol 2-dehydrogenase antibody
    • OTTHUMP00000161939 antibody
    • SDH antibody
    • Sorbitol dehydrogenase 1 antibody
    • Sorbitol dehydrogenase antibody
    • SORD 1 antibody
    • SORD antibody
    • SORD1 antibody
    see all

Anti-Sorbitol Dehydrogenase antibody images

  • Anti-Sorbitol Dehydrogenase antibody (ab113874) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size : 38 kDa

References for Anti-Sorbitol Dehydrogenase antibody (ab113874)

ab113874 has not yet been referenced specifically in any publications.

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