Anti-Sorbitol Dehydrogenase antibody (ab185705)

Overview

  • Product name
    Anti-Sorbitol Dehydrogenase antibody
    See all Sorbitol Dehydrogenase primary antibodies
  • Description
    Rabbit polyclonal to Sorbitol Dehydrogenase
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Full length protein corresponding to Human Sorbitol Dehydrogenase.
    Database link: Q00796

  • Positive control
    • HT29 cell lysate; mouse liver and kidney lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab185705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 38 kDa.
IHC-P 1/50 - 1/200.
ICC/IF Use at an assay dependent concentration.

Target

  • Function
    Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm.
  • Tissue specificity
    Expressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level).
  • Sequence similarities
    Belongs to the zinc-containing alcohol dehydrogenase family.
  • Cellular localization
    Mitochondrion membrane. Cell projection > cilium > flagellum. Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
  • Information by UniProt
  • Database links
  • Alternative names
    • DHSO_HUMAN antibody
    • L iditol 2 dehydrogenase antibody
    • L-iditol 2-dehydrogenase antibody
    • OTTHUMP00000161939 antibody
    • SDH antibody
    • Sorbitol dehydrogenase 1 antibody
    • Sorbitol dehydrogenase antibody
    • SORD 1 antibody
    • SORD antibody
    • SORD1 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat lung tissue labelling Sorbitol Dehydrogenase with ab185705 at 1/200. Magnification: 200x.
  • Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab185705. Blue DAPI for nuclear staining.
  • All lanes : Anti-Sorbitol Dehydrogenase antibody (ab185705) at 1/500 dilution

    Lane 1 : HT29 cell lysate
    Lane 2 : mouse liver lysate
    Lane 3 : mouse kidney lysate


    Predicted band size : 38 kDa

References

ab185705 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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