Overview

  • Product name
  • Description
    Rabbit polyclonal to SORBS1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human, Chinese hamster
  • Immunogen

    Synthetic peptide corresponding to Human SORBS1 aa 869-896 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q9BX66

  • Positive control
    • MDA-MB231 cell line lysate CHO cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab107531 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 143 kDa.

Target

  • Function
    Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.
  • Tissue specificity
    Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
  • Sequence similarities
    Contains 3 SH3 domains.
    Contains 1 SoHo domain.
  • Post-translational
    modifications
    O-glycosylated.
  • Cellular localization
    Cell junction > adherens junction. Cell membrane. Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.
  • Information by UniProt
  • Database links
  • Alternative names
    • c-Cbl-associated protein antibody
    • CAP antibody
    • CBL Associated Protein antibody
    • Ponsin antibody
    • SH3 domain protein 5 antibody
    • SH3D5 antibody
    • SH3P12 antibody
    • Sorbin and SH3 Domain Containing 1 antibody
    • Sorbin and SH3 domain-containing protein 1 antibody
    • Sorbs1 antibody
    • SRBS1_HUMAN antibody
    see all

Images

  • Anti-SORBS1 antibody (ab107531) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

    Predicted band size : 143 kDa
  • Anti-SORBS1 antibody (ab107531) at 1/100 dilution + CHO cell line lysate at 35 µg

    Predicted band size : 143 kDa

References

ab107531 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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