Recombinant fragment: VLRVLDQFQV MPLQFSKELD AYNPNTPEWR EDVGLVVTRL LSKETSVPQE LLVTVVKPGL PTLADLYVLL PPPRPTRKRS LSSDKRLAAI QQVLNAQKI, corresponding to amino acids 952-1050 of human SORCS2 (NP_065828) with a proprietary tag.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 128 kDa.
Use at an assay dependent dilution.
RelevanceSORCS2 is a member of the vacuolar protein sorting 10 (VPS10) domain containing receptor protein family. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. These proteins are strongly expressed in the central nervous system.
Cellular localizationMembrane; Single pass type I membrane protein.