Overview

  • Product nameAnti-SOSTDC1 antibody
    See all SOSTDC1 primary antibodies
  • Description
    Rabbit polyclonal to SOSTDC1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human SOSTDC1 (internal sequence).

  • Positive control
    • In Western Blot, this antibody gave a positive signal in human breast tissue lysate and in human, mouse and rat kidney tissue lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab56079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 23 kDa).
ELISA Use at an assay dependent dilution.

Target

  • FunctionMay be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
  • Tissue specificityHighly expressed in kidney and weakly in lung.
  • Sequence similaritiesBelongs to the sclerostin family.
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • CDA019 antibody
    • DKFZp564D206 antibody
    • Ectodermal BMP inhibitor antibody
    • Ectodin antibody
    • sclerostin domain containing 1 antibody
    • Sclerostin domain containing protein 1 antibody
    • Sclerostin domain-containing protein 1 antibody
    • SOSD1_HUMAN antibody
    • Sostdc1 antibody
    • USAG-1 antibody
    • USAG1 antibody
    • Uterine sensitization associated gene 1 protein antibody
    • Uterine sensitization-associated gene 1 protein antibody
    • Wise antibody
    see all

Anti-SOSTDC1 antibody images

  • All lanes : Anti-SOSTDC1 antibody (ab56079) at 1 µg/ml

    Lane 1 : Human kidney tissue lysate - total protein (ab30203)
    Lane 2 : Human breast tissue lysate - total protein (ab30090)
    Lane 3 : Kidney (Mouse) Tissue Lysate
    Lane 4 : Kidney (Rat) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 23 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)


    Exposure time : 4 minutes

References for Anti-SOSTDC1 antibody (ab56079)

ab56079 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry free floating
Sample Mouse Tissue sections (E13.5 wild-type whole salivary gland)
Specification E13.5 wild-type whole salivary gland
Username

Dr. Isabelle Miletich

Verified customer

Submitted Jun 04 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"