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Rabbit polyclonal to SOX18
Predicted to work with:
Mouse, Rat, Guinea pig, Cow, Dog, Pig
A region within a synthetic peptide: QPPPEPFPAA SGSARAFREL PPLGAEFDGL GLPTPERSPL DGLEPGEAAF, corresponding to internal sequence amino acids 181-230 of Human SOX18
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 2 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 41 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site.
Involvement in disease
Defects in SOX18 are the cause of hypotrichosis-lymphedema-telangiectasia syndrome (HLTS) [MIM:607823].
Contains 1 HMG box DNA-binding domain.
Contains 1 Sox C-terminal domain.
Information by UniProt
SOX 18 antibody
Western blot - SOX18 antibody (ab23342)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"