Recombinant
RabMAb

Anti-SOX18 antibody [EPR2837(2)] (ab109194)

Overview

  • Product name
    Anti-SOX18 antibody [EPR2837(2)]
    See all SOX18 primary antibodies
  • Description
    Rabbit monoclonal [EPR2837(2)] to SOX18
  • Tested applications
    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human SOX18.

  • Positive control
    • K562, Human stomach, Jurkat, and HeLa cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab109194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
IHC-P 1/100 - 1/250. Antigen retrieval is recommended.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Function
      Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site.
    • Involvement in disease
      Defects in SOX18 are the cause of hypotrichosis-lymphedema-telangiectasia syndrome (HLTS) [MIM:607823].
    • Sequence similarities
      Contains 1 HMG box DNA-binding domain.
      Contains 1 Sox C-terminal domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • HLTS antibody
      • SOX 18 antibody
      • Sox18 antibody
      • SOX18_HUMAN antibody
      • SRY (sex determining region Y) box 18 antibody
      • SRY box 18 antibody
      • Transcription factor SOX 18 antibody
      • Transcription factor SOX-18 antibody
      see all

    Images

    • All lanes : Anti-SOX18 antibody [EPR2837(2)] (ab109194) at 1/1000 dilution

      Lane 1 : K562 cell lysate
      Lane 2 : Human stomach cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 41 kDa
      Observed band size : 41 kDa

    References

    ab109194 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab109194.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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