Overview

  • Product name
    Anti-SOX6 antibody [155C5a]
    See all SOX6 primary antibodies
  • Description
    Mouse monoclonal [155C5a] to SOX6
  • Tested applications
    Suitable for: ICC/IF, WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human) from the C-terminal end (Accession number: NM_033326)

  • Positive control
    • HeLa cells

Properties

Applications

Our Abpromise guarantee covers the use of ab84880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 93 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • Function
    Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.
  • Tissue specificity
    Expressed in a wide variety of tissues, most abundantly in skeletal muscle.
  • Sequence similarities
    Contains 1 HMG box DNA-binding domain.
  • Post-translational
    modifications
    Sumoylation inhibits the transcriptional activity.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HSSOX 6 antibody
    • HSSOX6 antibody
    • SOX 6 antibody
    • sox6 antibody
    • SOX6_HUMAN antibody
    • SOXD antibody
    • SRY (sex determining region Y) box 6 antibody
    • SRY box 6 antibody
    • SRY box containing gene 6 antibody
    • Transcription factor SOX 6 antibody
    • Transcription factor Sox-6 antibody
    • Transcription factor SOX6 antibody
    see all

Images

  • Anti-SOX6 antibody [155C5a] (ab84880) + immunizing recombinant protein

    Predicted band size : 93 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)
  • Immunostaining analysis in HeLa cells using ab84880. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X 100 in PBS.

References

ab84880 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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