Overview

  • Product name
  • Description
    Rabbit polyclonal to SPAG17
  • Tested applications
    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence corresponding to amino acids 442-516 (SVPLILHCML EQVVATEEDL VPPSLREPSP RADGLDHRIA AHIVSLLPSL CLSEREKKNL HDIFLSEEEN ESKAV) of Human SPAG17.

  • Positive control
    • Human fallopian tube tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab122003 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Seems to be important for the structural integrity of the central apparatus of the sperm axoneme.
  • Tissue specificity
    Highly expressed in testis. Expressed in organs that contain cilia-bearing cells including brain, oviduct, lung, and uterus.
  • Cellular localization
    Cytoplasm. Cytoplasm > cytoskeleton > flagellum axoneme. Detected in the cytoplasm of round spermatids and in condensing spermatids. Localized to the central pair of the sperm flagellar axoneme. Colocalizes with SPAG6 on microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ34497 antibody
    • PF6 antibody
    • Projection protein PF6 homolog antibody
    • RP4 776P7.2 antibody
    • SPAG17 antibody
    • Sperm-associated antigen 17 antibody
    • SPG17_HUMAN antibody
    see all

Images

  • ab121003, at a 1/10 dilution, staining SPAG17 in paraffin-embedded Human fallopian tube tissue by Immunohistochemistry.

References

ab122003 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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