Anti-SPARC antibody [RM0130-5F41] (ab86467)

Overview

  • Product nameAnti-SPARC antibody [RM0130-5F41]
    See all SPARC primary antibodies
  • Description
    Rat monoclonal [RM0130-5F41] to SPARC
  • Tested applicationsSuitable for: ELISA, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant full length Mouse protein

Properties

Applications

Our Abpromise guarantee covers the use of ab86467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
IHC-Fr
  • Application notesDirect ELISA: 1/400 - 1/1000.
    IHC-Fr: 1/50 - 1/200.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAppears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
    • Sequence similaritiesBelongs to the SPARC family.
      Contains 1 EF-hand domain.
      Contains 1 follistatin-like domain.
      Contains 1 Kazal-like domain.
    • Developmental stageExpressed at high levels in tissues undergoing morphogenesis, remodeling and wound repair.
    • Cellular localizationSecreted > extracellular space > extracellular matrix > basement membrane. In or around the basement membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AA517111 antibody
      • Basement membrane protein 40 antibody
      • Basement-membrane protein 40 antibody
      • BM 40 antibody
      • BM-40 antibody
      • BM40 antibody
      • Cysteine rich protein antibody
      • hm:zeh0062 antibody
      • MGC128090 antibody
      • OI17 antibody
      • ON antibody
      • Osteonectin antibody
      • Secreted acidic cystein rich glycoprotein antibody
      • Secreted protein acidic and rich in cysteine antibody
      • Secreted protein acidic cysteine rich (osteonectin) antibody
      • Secreted protein acidic cysteine rich antibody
      • SPARC antibody
      • SPRC antibody
      • SPRC_HUMAN antibody
      see all

    References for Anti-SPARC antibody [RM0130-5F41] (ab86467)

    ab86467 has not yet been referenced specifically in any publications.

    Product Wall

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    The catalogue number is ab95462; http://www.abcam.com/Alkaline-Phosphatase-antibody-ab95462.html

    or

    ab113652; http://www.abcam.com/Alkaline-Phosphatase-antibody-SPM372-ab113652.html

    The c...

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    Thank you for contacting us.

    Please check the online datasheets ab64255 and ab64256 are already secondary antibodies.

    I suppose customer is looking for secondary antibody to ab86467. Please recommend them following; ab97057; http://ww...

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    Thank you for contacting us.

    We do not have Rat monoclonal anti BAP antibody, we however have mouse and rabbit monoclonal if customer is interested I can send the catalogue numbers.

    The Osteonectin antibody we have is ab86867; http://...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"