Overview

  • Product name
  • Description
    Mouse polyclonal to SPC25
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human SPC25 protein (NP_065726.1).

  • Positive control
    • Human kidney tissue lysate; SPC25 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab89028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 26 kDa.

Target

  • Function
    Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
  • Sequence similarities
    Belongs to the SPC25 family.
  • Cellular localization
    Nucleus. Chromosome > centromere > kinetochore. Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.
  • Information by UniProt
  • Database links
  • Alternative names
    • AD024 antibody
    • hSpc25 antibody
    • Kinetochore protein Spc25 antibody
    • SPBC25 antibody
    • SPC25 antibody
    • SPC25_HUMAN antibody
    • spindle pole body component 25 homolog antibody
    see all

Images

References

ab89028 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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