Tissue specificityExpressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.
Sequence similaritiesBelongs to the spectrin family. Contains 2 CH (calponin-homology) domains. Contains 1 PH domain. Contains 31 spectrin repeats.
Cellular localizationCytoplasm > cytoskeleton. Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.