Overview

  • Product nameAnti-Spermine synthase antibody
    See all Spermine synthase primary antibodies
  • Description
    Rabbit polyclonal to Spermine synthase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant protein of Human Spermine synthase amino acids 1-299 (NP_004586.2).

  • Positive control
    • Hela cell line lysate, Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab107536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

Target

  • FunctionRequired for normal viability, growth and fertility.
  • PathwayAmine and polyamine biosynthesis; spermine biosynthesis; spermine from spermidine: step 1/1.
  • Involvement in diseaseDefects in SMS are the cause of Snyder-Robinson syndrome (SRS) [MIM:309583]; also known as X-linked mental retardation Snyder-Robinson type. SRS is characterized by moderate intellectual deficit, hypotonia, an unsteady gait, osteoporosis, kyphoscoliosis and facial asymmetry. Transmission is X-linked recessive.
  • Sequence similaritiesBelongs to the spermidine/spermine synthase family.
  • DomainComposed of 3 domains: the N-terminal domain has structural similarity to S-adenosylmethionine decarboxylase, the central domain is made up of four beta strands and the C-terminal domain is similar in structure to spermidine synthase. The N- and C-terminal domains are both required for activity.
  • Information by UniProt
  • Database links
  • Alternative names
    • MRSR antibody
    • SMS antibody
    • Snyder Robinson X linked mental retardation syndrome antibody
    • Spermidine aminopropyltransferase antibody
    • Spermine synthase antibody
    • SPMSY antibody
    • SpS antibody
    • SPSY_HUMAN antibody
    • SRS antibody
    see all

Anti-Spermine synthase antibody images

  • Anti-Spermine synthase antibody (ab107536) at 1/100 dilution + Hela cell line lysate at 35 µg

    Predicted band size : 41 kDa

References for Anti-Spermine synthase antibody (ab107536)

ab107536 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"