Overview

  • Product name
  • Description
    Rabbit polyclonal to SPFH2
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 278-339 (PEYLQLMKYK AIASNSKIYF GKDIPNMFMD SAGSVSKQFE GLADKLSFGL EDEPLETATK EN) of Human SPFH2 (NP_009106).

  • Positive control
    • HeLaS3 whole cell lysate; Endo mitral OVCA; 293T, A431, H1299, HepG2 and Raji cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab96591 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 38 kDa.
IHC-P 1/100.

Target

  • Function
    Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the band 7/mec-2 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C8orf2 antibody
    • Chromosome 8 open reading frame 2 antibody
    • Endoplasmic reticulum lipid raft associated protein 2 antibody
    • Endoplasmic reticulum lipid raft-associated protein 2 antibody
    • ER lipid raft associated 2 antibody
    • ERLIN 2 antibody
    • Erlin-2 antibody
    • ERLIN2 antibody
    • ERLN2_HUMAN antibody
    • HGNC:1356 antibody
    • MGC87072 antibody
    • NET32 antibody
    • SPFH 2 antibody
    • SPFH domain containing protein 2 antibody
    • SPFH domain family member 2 antibody
    • SPFH domain-containing protein 2 antibody
    • SPFH2 antibody
    • SPG18 antibody
    • Stomatin prohibitin flotillin HflC/K domain containing protein 2 antibody
    • Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded endo mitral OVCA using ab96591 at 1/100 dilution.
  • Anti-SPFH2 antibody (ab96591) at 1/500 dilution + HeLaS3 whole cell lysate at 30 µg

    Predicted band size : 38 kDa

References

ab96591 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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