Overview

  • Product name
    Anti-SPG20 antibody
  • Description
    Rabbit polyclonal to SPG20
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the N terminal region of Human SPG20 conjugated to KLH (NP_055902.1).

  • Positive control
    • NCI-H460 cell line lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab94950 was purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab94950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 73 kDa.

Target

  • Relevance
    SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.
  • Database links
  • Alternative names
    • SPARTIN antibody
    • Spastic paraplegia 20 (Troyer syndrome) antibody
    • TAHCCP1 antibody
    • Trans activated by hepatitis C virus core protein 1 antibody

Images

  • Anti-SPG20 antibody (ab94950) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

    Predicted band size : 73 kDa

References

This product has been referenced in:
  • Douglas JN  et al. Antibodies to the RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein A1 Colocalize to Stress Granules Resulting in Altered RNA and Protein Levels in a Model of Neurodegeneration in Multiple Sclerosis. J Clin Cell Immunol 7:402 (2016). WB . Read more (PubMed: 27375925) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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