Anti-Sphingomyelin Synthase 2 antibody (ab102941)

Overview

  • Product nameAnti-Sphingomyelin Synthase 2 antibody
    See all Sphingomyelin Synthase 2 primary antibodies
  • Description
    Rabbit polyclonal to Sphingomyelin Synthase 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the C terminal region of Human Sphingomyelin Synthase 2 (UniProt ID: Q8NHU3).

  • Positive control
    • HepG2 cell line lysates; Mouse spleen tissue lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab102941 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.

Target

  • FunctionBidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Does not function strictly as a SM synthase. Required for cell growth.
  • Tissue specificityBrain, heart, kidney, liver, muscle and stomach.
  • Sequence similaritiesBelongs to the sphingomyelin synthase family.
  • Post-translational
    modifications
    Palmitoylated on Cys-331, Cys-332, Cys-343 and Cys-348; which plays an important role in plasma membrane localization.
  • Cellular localizationCell membrane. Golgi apparatus membrane. Predominantly plasma membrane, some in Golgi apparatus.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC26963 antibody
    • Phosphatidylcholine:ceramide cholinephosphotransferase 2 antibody
    • SGMS 2 antibody
    • Sgms2 antibody
    • SM synthase antibody
    • SMS 2 antibody
    • SMS2 antibody
    • SMS2_HUMAN antibody
    • Sphingomyelin synthase 2 antibody
    see all

Anti-Sphingomyelin Synthase 2 antibody images

  • Anti-Sphingomyelin Synthase 2 antibody (ab102941) at 1/100 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 42 kDa
  • Anti-Sphingomyelin Synthase 2 antibody (ab102941) at 1/100 dilution + Mouse spleen tissue lysates at 35 µg

    Predicted band size : 42 kDa

References for Anti-Sphingomyelin Synthase 2 antibody (ab102941)

ab102941 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab102941.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"