Human Predicted to work with:
Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
Synthetic peptide corresponding to a region within internal sequence amino acids 287-336 (THKYAPFIII GLHLALGIFS FTLDTWSTSR GDTAEILGSG AGIACGSHVT) of Human sphingosine-1-phosphate phosphatase 1 (NP_110418)
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
RelevanceSphingosine-1-phosphate phosphatase 1 (Spp1) regulates intracellular and extracellular sphingosine 1 phosphate(S1P)levels. It belongs to the type 2 lipid phosphate phosphatase family and is expressed in the endoplasmic reticulum (ER) membrane.