Overview

  • Product nameAnti-SPHK1 antibody
    See all SPHK1 primary antibodies
  • Description
    Mouse monoclonal to SPHK1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-385 of Human SPHK1

Properties

Applications

Our Abpromise guarantee covers the use of ab56414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCatalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
    • Tissue specificityWidely expressed with highest levels in adult liver, kidney, heart and skeletal muscle.
    • Sequence similaritiesContains 1 DAGKc domain.
    • Information by UniProt
    • Database links
    • Alternative names
      • SK 1 antibody
      • SK1 antibody
      • Sphingosine kinase 1 antibody
      • SPHK 1 antibody
      • SPHK antibody
      • Sphk1 antibody
      • SPHK1_HUMAN antibody
      • SPK antibody
      • SPK 1 antibody
      see all

    Anti-SPHK1 antibody images



    • Predicted band size : 43 kDa
      SPHK1 antibody (ab56414) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    References for Anti-SPHK1 antibody (ab56414)

    This product has been referenced in:
    • Gellings Lowe N  et al. Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts. Cardiovasc Res 82:303-12 (2009). Read more (PubMed: 19228708) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab56414.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"